Articles listed by date
Results for 22 December 2020
Research Highlight | December 22, 2020
Seeking international standards for colon cancer surgery
A TRI-sponsored trial seeks to establish best practices for colorectal surgeons around the world
Results for 15 December 2020
Research Highlight | December 15, 2020
Electrical stimulation doesn’t seem to hasten stroke recovery
Device may help wearers, but trial indicates it doesn’t aid long-term rehabilitation
Results for 13 November 2020
Research Highlight | November 13, 2020
Reassessing targets for managing kidney disease
Trial suggests doctors in Japan may be overtreating anemia in patients with non-diabetic kidney failure
Results for 18 September 2020
Research Highlight | September 18, 2020
Taking a whole-body approach to cancer screening
Whole-body screens that include positron-emission tomography can identify cancers that may otherwise go undetected
Results for 19 August 2020
Research Highlight | August 19, 2020
New life for old heart drug
Clinicians may have abandoned a lipid-lowering drug too soon, suggests a new study, which finds evidence for its disfavor lacking.
Results for 6 July 2020
Research Highlight | July 6, 2020
The ABCs of dementia
A scale could evaluate degrees of dementia, and plot the condition’s development more accurately.
Results for 21 April 2020
Feature | April 21, 2020
Working together to accelerate medical innovation
Chinese and Japanese participants gathered in Chengdu to discuss advanced medicine
Results for 30 January 2020
Research Highlight | January 30, 2020
Weakness in conventional allergy treatment revealed
Raised levels of an antibody thought to indicate tolerance to food allergens in people with established allergies suggests commonly accepted treatments are not universally effective for adults.
Results for 23 January 2020
Research Highlight | January 23, 2020
Neuroendovascular therapy on the rise in aging Japan
A minimally invasive surgery for vascular conditions in the brain and spine is safe, even for the elderly, as long as patients are chosen with care
Results for 20 December 2019
The Principles Of Regenerative Medicine | December 20, 2019
Preface
Masanori Fukushima, TRI Director, Foundation for Biomedical Research and Innovation at Kobe, Translational Research Center for Medical Innovation (TRI)
The Principles Of Regenerative Medicine | December 20, 2019
An overview of regenerative medicine: its principles and the scope of the current revolution
Masanori Fukushima, TRI Director, Foundation for Biomedical Research and Innovation at Kobe, Translational Research Center for Medical Innovation (TRI)
The Principles Of Regenerative Medicine | December 20, 2019
Stem-cell therapy 1: Potential treatment of cerebral infarcts and spinal cord injury with mesenchymal stem cell transplantation
Osamu Honmou
The Principles Of Regenerative Medicine | December 20, 2019
Stem-cell therapy 2: Tissue regeneration by Muse cells after acute myocardial infarction
Shinya Minatoguchi*†, Yoshihisa Yamada‡, Shingo Minatoguchi‡, Toshiki Tanaka‡, Atsushi Mikami*, Shohei Wakao§, Yoshihiro Kushida§ and Mari Dezawa§
The Principles Of Regenerative Medicine | December 20, 2019
Stem-cell therapy 3: Cell-based neovascularization therapy for peripheral arterial disease
Yasuyuki Fujita and Atsuhiko Kawamoto
The Principles Of Regenerative Medicine | December 20, 2019
Tissue engineering 1: Autologous transplantation of peripheral blood CD34+ cells in patients with femoral and tibial fracture non-union
Ryosuke Kuroda, Tomoyuki Matsumoto and Takahiro Niikura
The Principles Of Regenerative Medicine | December 20, 2019
Tissue engineering 2: Transplantation of cultivated autologous oral mucosal epithelial sheets in order to restore sight
Chie Sotozono*, Tsutomu Inatomi*†, Takahiro Nakamura*, Noriko Koizumi‡, Kojiro Imai§, Shigeru Kinoshita*| , Yasuko Kimura¶ , Masahiro J. Go¶ and Masanori Fukushima¶
The Principles Of Regenerative Medicine | December 20, 2019
Tissue engineering 3: A tissue-engineering approach to tympanic membrane regeneration
Shinichi Kanemaru
Feature | December 20, 2019
Medical technology advancing along key fronts
Disruptive strategies for treating diseases, new medical devices and big data are set to transform medical treatment
Research Highlight | December 20, 2019
New hope for stroke and spinal injury
Treatment based on stem cells aims to actively repair brain and spinal cord tissue damaged by stroke or spinal cord injury
Research Highlight | December 20, 2019
Cells could help heal a broken heart
A recently discovered cell type may help improve the long-term outlook after heart attack
Research Highlight | December 20, 2019
Reducing risk to life and limb through stem cell therapy
Stem cells offer hope for patients with critical limb ischemia, a potentially fatal circulatory disease of the legs
Research Highlight | December 20, 2019
Stem cells deployed to unite broken bones that refuse to heal
Stem cell therapy assists healing broken bones in combination with bone graft surgery
Research Highlight | December 20, 2019
Reducing cornea damage by transplanting cells from mouth
Transplanting sheets of cells grown in the lab onto the eye improves vision in patients suffering from severe disorders of the surface of their eyes
Research Highlight | December 20, 2019
Stimulating stem cells to heal burst eardrums
A sponge in the ear could become a safer and more convenient treatment for burst eardrums
Results for 30 October 2019
Infographic | October 30, 2019
Prostate cancer
People with cancer of the prostate currently have numerous treatment options available to them. But one of the most established, a type of radiation therapy known as brachytherapy, seems to be falling out of favour with clinicians.
Results for 23 August 2019
Research Highlight | August 23, 2019
A budding prognostic tool
Analysis of the invasive front of colorectal tumours provides a useful prognostic factor to aid in treatment decisions
Results for 8 August 2019
Feature | August 8, 2019
Spinal cord treatment using stem cells
After a small-scale clinical trial, a promising stem-cell treatment for spinal cord injuries is now available in Japan
Results for 18 July 2019
Research Highlight | July 18, 2019
A checklist to predict need for care
Cognition questions on a widely used frailty assessment can help identify those who will soon require long-term care
Research Highlight | July 18, 2019
The value of a second opinion
A three-year nationwide study suggests that specialized pathologists should be consulted to confirm gastrointestinal stromal tumour diagnosis
Results for 11 March 2019
Research Highlight | March 11, 2019
Precise sorting of tumours may improve treatment
Close evaluation of colon cancer progression, and disease characteristics, could hone treatment options
Results for 21 December 2018
Feature | December 21, 2018
Producing fit and active centenarians
TRI is striving to enliven society by harnessing the power of regenerative medicine
Research Highlight | December 21, 2018
Preventing spinal cord injuries is a numbers game
A longitudinal investigation at the Hyogo Rehabilitation Center suggests that age-targeted preventative strategies could reduce the incidence of spinal cord injuries
Results for 20 December 2018
Infographic | December 20, 2018
Liver cirrhosis
Once thought to be irreversible, cirrhosis of the liver now seems treatable — and drug development is proceeding apace.
Results for 30 November 2018
Research Highlight | November 30, 2018
A stem cell fix for limbs
Patients with renal failure and blocked arteries in their legs respond favorably to a new kind of stem cell therapy
Research Highlight | November 30, 2018
Narrowing a treatment plan for asthma
Asthma attacks come in three forms, and each requires a different management approach
Results for 8 November 2018
Infographic | November 8, 2018
Ulcerative colitis
Ulcerative colitis is a debilitating and incurable condition. But researchers have found fresh angles of attack, and a host of upcoming treatments raise the prospect of a durable victory against this common form of inflammatory bowel disease.
Results for 12 October 2018
Research Highlight | October 12, 2018
Weighing the Asian response to statins and stroke risk
Understanding the long-term use of statins for preventing stroke recurrence in Asian patients
Research Highlight | October 12, 2018
Tight quality control pays off for prostate cancer treatment
Standardized nationwide staff training in prostate cancer treatment in Japan contributes to high patient survival rates
Results for 14 September 2018
Research Highlight | September 14, 2018
Validating biomarkers for Alzheimer’s disease across ethnicities
Are the markers of early Alzheimer’s disease similar across populations?
Research Highlight | September 14, 2018
Milk thistle extract could prevent cognitive decline in Alzheimer’s disease patients
Blocking amyloid assembly in blood vessels is a promising strategy for slowing dementia
Results for 23 August 2018
Feature | August 23, 2018
Collaborating against cancer
Convening for the fourth year, Japanese and Taiwanese academics continue to push forward together to tackle critical medical science issues.
Results for 25 July 2018
Research Highlight | July 25, 2018
Quick questionnaire for Alzheimer’s disease
A new questionnaire to help detect and monitor Alzheimer’s disease
Results for 13 June 2018
Feature | June 13, 2018
Casting a wider net for big data benefits
Embracing big data promises to expand the knowledge brought by clinical trials and lead to safer therapies
Research Highlight | June 13, 2018
Growth factor restores scarred vocal cords
A first-in-human clinical trial demonstrates the safety and efficacy of growth factor-based therapy for vocal fold scarring
Results for 2 May 2018
Research Highlight | May 2, 2018
Surgery brings on the smooth talk
A Japanese surgical procedure gives patients their voices back
Results for 19 April 2018
Feature | April 19, 2018
Launching a wealth of medical knowledge
An authoritative source of medical information for almost 120 years, the MSD manuals are now freely available online in Japanese
Results for 7 March 2018
Feature | March 7, 2018
Living well to a hundred and beyond
The public were given a preview of therapies that promise to preserve the quality of life of people well into old age
Feature | March 7, 2018
The harmony of standardized data
Translational and clinical research is hampered by the ‘dissonant notes’ of poor efficacy systems and a lack of data standards, claim researchers and policymakers. Fixing these problems can save lives.
Results for 14 December 2017
Infographic | December 14, 2017
Repairing the neural highway
The spinal cord rarely repairs itself when damaged, but ways of encouraging nerves to regrow are on the horizon.
Results for 30 November 2017
Research Highlight | November 30, 2017
Preventing stroke in Asian populations
A common cholesterol drug could help prevent certain types of strokes in Asian people
Results for 29 November 2017
Research Highlight | November 29, 2017
Repurposed drug could help clear toxic plaques in Alzheimer’s disease
Boosting the flow of blood to the brain could slow cognitive decline in patients.
Results for 26 October 2017
Feature | October 26, 2017
Stem cell therapies demonstrating their potential
CD34 positive stem cells could be used to treat a wide range of medical conditions
Research Highlight | October 26, 2017
A better view for healing hearts
An infrared imaging technique effectively facilitates stent insertion into blocked heart vessels
Infographic | October 26, 2017
Closing the gap
A bone fracture that fails to heal after initial treatment can lead to prolonged disability. Regenerative therapies might help to restart the bone-healing process, getting the people affected back in action.
Results for 23 August 2017
Infographic | August 23, 2017
Saving life and limb
Many people with critical limb ischaemia have no option but to have the affected limb amputated. Can regenerative medicine offer an alternative?
Results for 5 July 2017
Research Highlight | July 5, 2017
Saving limbs by growing new blood vessels
Stem cell therapy offers hope of rescuing blood-starved limbs
Results for 4 July 2017
Research Highlight | July 4, 2017
A stem cell fix for spinal injury
Stem cells derived from bone marrow could help people with damaged spinal cords to recover
Research Highlight | July 4, 2017
Stem cell therapy could help fractures heal better faster
A stem cell treatment offers a faster and less invasive way to fix fractured bones that have failed to heal
Research Highlight | July 4, 2017
Regenerative fix is music to the ears
A growth factor helps repair ruptured eardrums without invasive surgery
Feature | July 4, 2017
Clinical trials on trial
Poor standards in clinical trials waste time and money, and cost lives. Global cooperation is the only way to raise the bar.
Feature | July 4, 2017
From lab to clinic
TRI director Masanori Fukushima says considering disease mechanisms are the key to providing medicines to ease the journey into old age
Research Highlight | July 4, 2017
A bit of cheek restores sight
Cells transplanted from inside the mouth could restore sight in people blinded by disease, but practical challenges may hamper therapy delivery
Results for 21 June 2017
Infographic | June 21, 2017
Marching to a new beat
In the most severe cases, a ruptured eardrum can require surgery to put it right, but tissue-engineering techniques might provide a much simpler solution.
Results for 19 April 2017
Infographic | April 19, 2017
Let there be sight
Loss of the stem cells that constantly renew the surface of the cornea causes pain and, in some cases, blindness. Advances in transplantation and cell culture are helping to restore vision to even the most severely affected people.