© 2019 Hideki Ueno

A budding prognostic tool

Analysis of the invasive front of colorectal tumours provides a useful prognostic factor to aid in treatment decisions

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RESEARCH HIGHLIGHTS

A checklist to predict need for care

Cognition questions on a widely used frailty assessment can help identify those who will soon require long-term care

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The value of a second opinion

A three-year nationwide study suggests that specialized pathologists should be consulted to confirm gastrointestinal stromal tumour diagnosis

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Precise sorting of tumours may improve treatment

Close evaluation of colon cancer progression, and disease characteristics, could hone treatment options

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Preventing spinal cord injuries is a numbers game

A longitudinal investigation at the Hyogo Rehabilitation Center suggests that age-targeted preventative strategies could reduce the incidence of spinal cord injuries

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FEATURES

Spinal cord treatment using stem cells

After a small-scale clinical trial, a promising stem-cell treatment for spinal cord injuries is now available in Japan

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Producing fit and active centenarians

TRI is striving to enliven society by harnessing the power of regenerative medicine

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Collaborating against cancer

Convening for the fourth year, Japanese and Taiwanese academics continue to push forward together to tackle critical medical science issues.

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Casting a wider net for big data benefits

Embracing big data promises to expand the knowledge brought by clinical trials and lead to safer therapies

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INFOGRAPHICS

Liver cirrhosis

Once thought to be irreversible, cirrhosis of the liver now seems treatable — and drug development is proceeding apace.

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Ulcerative colitis

Ulcerative colitis is a debilitating and incurable condition. But researchers have found fresh angles of attack, and a host of upcoming treatments raise the prospect of a durable victory against this common form of inflammatory bowel disease.

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Repairing the neural highway

The spinal cord rarely repairs itself when damaged, but ways of encouraging nerves to regrow are on the horizon.

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Closing the gap

A bone fracture that fails to heal after initial treatment can lead to prolonged disability. Regenerative therapies might help to restart the bone-healing process, getting the people affected back in action.

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COLLABORATIONS WITH NATURE

cover

Liver cirrhosis: scar wars

Vol 564, S73 (20 December 2018)

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